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Flightless I exacerbation of inflammatory responses contributes to increased colonic damage in a mouse model of dextran sulphate sodium-induced ulcerative colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by cytokine driven inflammation that disrupts the mucosa and impedes intestinal structure and functions. Flightless I (Flii) is an immuno-modulatory protein is a member of the gelsolin family of actin-remodelling proteins...

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Detalles Bibliográficos
Autores principales:	Kopecki, Z., Yang, G., Treloar, S., Mashtoub, S., Howarth, G. S., Cummins, A. G., Cowin, A. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728368/ https://www.ncbi.nlm.nih.gov/pubmed/31488864 http://dx.doi.org/10.1038/s41598-019-49129-6

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