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Awareness and Current Therapeutics of Asthma

INTRODUCTION: Asthma is a serious allergic disorder of the respiratory system. It affects about 300 million people worldwide. This has a great burden on medical treatment. Several medicines are available, but they have many serious side effects. Therefore, there is a need to search for a new therape...

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Autores principales: Zainab, Rida, Akram, Muhammad, Daniyal, Muhammad, Riaz, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728691/
https://www.ncbi.nlm.nih.gov/pubmed/31523203
http://dx.doi.org/10.1177/1559325819870900
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author Zainab, Rida
Akram, Muhammad
Daniyal, Muhammad
Riaz, Muhammad
author_facet Zainab, Rida
Akram, Muhammad
Daniyal, Muhammad
Riaz, Muhammad
author_sort Zainab, Rida
collection PubMed
description INTRODUCTION: Asthma is a serious allergic disorder of the respiratory system. It affects about 300 million people worldwide. This has a great burden on medical treatment. Several medicines are available, but they have many serious side effects. Therefore, there is a need to search for a new therapeutic agent with no or minimal side effects while most economical for patients. In folk medicine, antiasthmatics herbal medicine has been used and showed potential therapeutic antiasthmatic efficacy due to the presence of potential bioactive compounds. METHODS: Different databases were searched (ie, Embase, PubMed, CBM, AMED, and CINAHL). We have reviewed the published data of the last 20 years. We used MeSH terms “asthma” herbal treatment of asthma, allopathic treatment of asthma, and treatment strategies for asthma. The traditional medicine was compared with modern medicine and the same pharmacotherapies alone or with placebo. The methodology was evaluated by using the GRADE summary of Finding tables and Cochrane Risk of Bias Tool. RESULTS: There have been some clear-cut indications toward the recognition of further molecular and cellular mechanisms of asthma. Most of them recommend a further target for treatment. The novel procedures, biologics, and pharmaceuticals are evaluated. Both allopathic and herbal treatments of asthma are effective. Due to none or lesser side effects, herbal medicines are safer than conventional medicine. CONCLUSION: The preliminary documentation of the plants discussed in the review show the presence of several secondary metabolites that are responsible for the management of asthma and its relevant complications. Further research studies are needed to identify the bioactive compounds from these plants that have potential efficacy to cure asthma, and clinically based studies are needed to search for a complete cure for this disease.
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spelling pubmed-67286912019-09-13 Awareness and Current Therapeutics of Asthma Zainab, Rida Akram, Muhammad Daniyal, Muhammad Riaz, Muhammad Dose Response Review INTRODUCTION: Asthma is a serious allergic disorder of the respiratory system. It affects about 300 million people worldwide. This has a great burden on medical treatment. Several medicines are available, but they have many serious side effects. Therefore, there is a need to search for a new therapeutic agent with no or minimal side effects while most economical for patients. In folk medicine, antiasthmatics herbal medicine has been used and showed potential therapeutic antiasthmatic efficacy due to the presence of potential bioactive compounds. METHODS: Different databases were searched (ie, Embase, PubMed, CBM, AMED, and CINAHL). We have reviewed the published data of the last 20 years. We used MeSH terms “asthma” herbal treatment of asthma, allopathic treatment of asthma, and treatment strategies for asthma. The traditional medicine was compared with modern medicine and the same pharmacotherapies alone or with placebo. The methodology was evaluated by using the GRADE summary of Finding tables and Cochrane Risk of Bias Tool. RESULTS: There have been some clear-cut indications toward the recognition of further molecular and cellular mechanisms of asthma. Most of them recommend a further target for treatment. The novel procedures, biologics, and pharmaceuticals are evaluated. Both allopathic and herbal treatments of asthma are effective. Due to none or lesser side effects, herbal medicines are safer than conventional medicine. CONCLUSION: The preliminary documentation of the plants discussed in the review show the presence of several secondary metabolites that are responsible for the management of asthma and its relevant complications. Further research studies are needed to identify the bioactive compounds from these plants that have potential efficacy to cure asthma, and clinically based studies are needed to search for a complete cure for this disease. SAGE Publications 2019-09-04 /pmc/articles/PMC6728691/ /pubmed/31523203 http://dx.doi.org/10.1177/1559325819870900 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Zainab, Rida
Akram, Muhammad
Daniyal, Muhammad
Riaz, Muhammad
Awareness and Current Therapeutics of Asthma
title Awareness and Current Therapeutics of Asthma
title_full Awareness and Current Therapeutics of Asthma
title_fullStr Awareness and Current Therapeutics of Asthma
title_full_unstemmed Awareness and Current Therapeutics of Asthma
title_short Awareness and Current Therapeutics of Asthma
title_sort awareness and current therapeutics of asthma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728691/
https://www.ncbi.nlm.nih.gov/pubmed/31523203
http://dx.doi.org/10.1177/1559325819870900
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