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Metformin prevents the pathological browning of subcutaneous white adipose tissue

OBJECTIVE: Browning, the conversion of white adipose tissue (WAT) to a beige phenotype, has gained interest as a strategy to induce weight loss and improve insulin resistance in metabolic disorders. However, for hypermetabolic conditions stemming from burn trauma or cancer cachexia, browning is thou...

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Detalles Bibliográficos
Autores principales: Auger, Christopher, Knuth, Carly M., Abdullahi, Abdikarim, Samadi, Osai, Parousis, Alexandra, Jeschke, Marc G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728757/
https://www.ncbi.nlm.nih.gov/pubmed/31668383
http://dx.doi.org/10.1016/j.molmet.2019.08.011