Cargando…

Metformin prevents the pathological browning of subcutaneous white adipose tissue

OBJECTIVE: Browning, the conversion of white adipose tissue (WAT) to a beige phenotype, has gained interest as a strategy to induce weight loss and improve insulin resistance in metabolic disorders. However, for hypermetabolic conditions stemming from burn trauma or cancer cachexia, browning is thou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Auger, Christopher, Knuth, Carly M., Abdullahi, Abdikarim, Samadi, Osai, Parousis, Alexandra, Jeschke, Marc G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728757/ https://www.ncbi.nlm.nih.gov/pubmed/31668383 http://dx.doi.org/10.1016/j.molmet.2019.08.011

Ejemplares similares

Adipose browning response to burn trauma is impaired with aging
por: Abdullahi, Abdikarim, et al.
Publicado: (2021)

Browning of white adipose tissue after a burn injury promotes hepatic steatosis and dysfunction
por: Abdullahi, Abdikarim, et al.
Publicado: (2019)

Burn Induces Browning of the Subcutaneous White Adipose Tissue in Mice and Humans
por: Patsouris, David, et al.
Publicado: (2015)

48 Metformin Rescues the Aging-induced Failure of Post-burn White Adipose Browning
por: Barayan, Dalia, et al.
Publicado: (2022)

Metformin adapts its cellular effects to bioenergetic status in a model of metabolic dysfunction
por: Auger, Christopher, et al.
Publicado: (2018)

Serum amlyoid A: An inflammatory adipokine mediating postburn outcomes
por: Abdullahi, Abdikarim, et al.
Publicado: (2021)

Endoplasmic reticulum stress in adipose tissue augments lipolysis
por: Bogdanovic, Elena, et al.
Publicado: (2015)

Transdermal Delivery of Metformin Using Dissolving Microneedles and Iontophoresis Patches for Browning Subcutaneous Adipose Tissue
por: Abbasi, Mehrnaz, et al.
Publicado: (2022)

Egr1 deficiency induces browning of inguinal subcutaneous white adipose tissue in mice
por: Milet, Cécile, et al.
Publicado: (2017)

Sexual Dimorphism in Brown Adipose Tissue Activation and White Adipose Tissue Browning
por: Gómez-García, Iker, et al.
Publicado: (2022)

White adipose tissue browning and obesity
por: Cui, Xiao-Bing, et al.
Publicado: (2017)

Regulation of glycolysis and the Warburg effect in wound healing
por: Vinaik, Roohi, et al.
Publicado: (2020)

Browning Subcutaneous White Adipose Tissue Using Transdermal Delivery of ASC-Targeting Peptide and Resveratrol Conjugate
por: Abbasi, Mehrnaz, et al.
Publicado: (2022)

Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice
por: Laiglesia, Laura M., et al.
Publicado: (2023)

Adipose‐specific ATGL ablation reduces burn injury‐induced metabolic derangements in mice
por: Kaur, Supreet, et al.
Publicado: (2021)

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice
por: Weiner, Juliane, et al.
Publicado: (2016)

Humans and Mice Display Opposing Patterns of “Browning” Gene Expression in Visceral and Subcutaneous White Adipose Tissue Depots
por: Zuriaga, Maria A., et al.
Publicado: (2017)

Effects of metformin on metabolism of white and brown adipose tissue in obese C57BL/6J mice
por: Yuan, Tao, et al.
Publicado: (2019)

Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT)
por: Dong, Haijun, et al.
Publicado: (2023)

HOXC10 suppresses browning of white adipose tissues
por: Ng, Yvonne, et al.
Publicado: (2017)

DEPP Deficiency Contributes to Browning of White Adipose Tissue
por: Guo, Fusheng, et al.
Publicado: (2022)

Adipose Tissue Metabolic Function and Dysfunction: Impact of Burn Injury
por: Kaur, Supreet, et al.
Publicado: (2020)

Quantifying Biochemical Alterations in Brown and Subcutaneous White Adipose Tissues of Mice Using Fourier Transform Infrared Widefield Imaging
por: Aboualizadeh, Ebrahim, et al.
Publicado: (2017)

Alcohol, White Adipose Tissue, and Brown Adipose Tissue: Mechanistic Links to Lipogenesis and Lipolysis
por: Li, Qing, et al.
Publicado: (2023)

Differential remodeling of subcutaneous white and interscapular brown adipose tissue by long-term exercise training in aged obese female mice
por: Félix-Soriano, Elisa, et al.
Publicado: (2023)

Metformin Mitigates Fibrosis and Glucose Intolerance Induced by Doxorubicin in Subcutaneous Adipose Tissue
por: Biondo, Luana A., et al.
Publicado: (2018)

Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling
por: Bauters, Dries, et al.
Publicado: (2017)

MitoNEET-Mediated Effects on Browning of White Adipose Tissue
por: Kusminski, Christine M., et al.
Publicado: (2014)

Phytochemicals as novel agents for the induction of browning in white adipose tissue
por: Azhar, Yusra, et al.
Publicado: (2016)

Fat Grafting Can Induce Browning of White Adipose Tissue
por: Hoppela, Erika, et al.
Publicado: (2018)

Fibroblast Growth Factor 21 and Browning of White Adipose Tissue
por: Cuevas-Ramos, Daniel, et al.
Publicado: (2019)

Regulatory microRNAs in Brown, Brite and White Adipose Tissue
por: Gharanei, Seley, et al.
Publicado: (2020)

ASK1 inhibits browning of white adipose tissue in obesity
por: Lucchini, Fabrizio C., et al.
Publicado: (2020)

Cold-Induced Changes in Gene Expression in Brown Adipose Tissue, White Adipose Tissue and Liver
por: Shore, Andrew M., et al.
Publicado: (2013)

Silk Hydrogel-Mediated Delivery of Bone Morphogenetic Protein 7 Directly to Subcutaneous White Adipose Tissue Increases Browning and Energy Expenditure
por: Townsend, Kristy L., et al.
Publicado: (2022)

Angiotensin type 2 receptor activation promotes browning of white adipose tissue and brown adipogenesis
por: Than, Aung, et al.
Publicado: (2017)

OR04-05 MYOD1 Is Associated with Eosinophil-Mediated Browning of Subcutaneous Adipose Tissue
por: Li, Ting, et al.
Publicado: (2020)

Fetal development of subcutaneous white adipose tissue is dependent on Zfp423
por: Shao, Mengle, et al.
Publicado: (2016)

SCD1 promotes lipid mobilization in subcutaneous white adipose tissue
por: Zou, Ying, et al.
Publicado: (2020)

Regulation of gene expression by FSP27 in white and brown adipose tissue
por: Li, De, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_t0s3ogq8095gm8352f79jfbhh5