Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production

OBJECTIVE: Enteroendocrine cells (EECs) of the gastro-intestinal tract sense gut luminal factors and release peptide hormones or serotonin (5-HT) to coordinate energy uptake and storage. Our goal is to decipher the gene regulatory networks controlling EECs specification from enteroendocrine progenit...

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Detalles Bibliográficos
Autores principales: Piccand, Julie, Vagne, Constance, Blot, Florence, Meunier, Aline, Beucher, Anthony, Strasser, Perrine, Lund, Mari L., Ghimire, Sabitri, Nivlet, Laure, Lapp, Céline, Petersen, Natalia, Engelstoft, Maja S., Thibault-Carpentier, Christelle, Keime, Céline, Correa, Sara Jimenez, Schreiber, Valérie, Molina, Nacho, Schwartz, Thue W., De Arcangelis, Adèle, Gradwohl, Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728766/
https://www.ncbi.nlm.nih.gov/pubmed/31668390
http://dx.doi.org/10.1016/j.molmet.2019.08.007

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