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Effect of P21‐activated kinase 1 (PAK‐1) inhibition on cancer cell growth, migration, and invasion

P21‐activated kinase‐1 (PAK‐1) is a serine/threonine kinase involved in multiple signaling pathways that mediate cellular functions such as cytoskeletal motility, cell proliferation, and survival. PAK‐1 expression is altered in various cancers, including prostate and breast. Our recent studies showe...

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Detalles Bibliográficos
Autores principales: Najahi‐Missaoui, Wided, Quach, Nhat D., Jenkins, Amber, Dabke, Isha, Somanath, Payaningal R., Cummings, Brian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728842/
https://www.ncbi.nlm.nih.gov/pubmed/31516713
http://dx.doi.org/10.1002/prp2.518