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The Nrf2 activator RTA-408 attenuates osteoclastogenesis by inhibiting STING dependent NF-κb signaling

The dysregulation of ROS production and osteoclastogenesis is involved in the progress of osteoporosis. To identify novel and effective targets to treat this disease, it is important to explore the underlying mechanisms. In our study, we firstly tested the effect of the Nrf2 activator RTA-408, a nov...

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Detalles Bibliográficos
Autores principales:	Sun, Xuewu, Xie, Ziang, Hu, Bin, Zhang, Boya, Ma, Yan, Pan, Xin, Huang, Hai, Wang, Jiying, Zhao, Xiangde, Jie, Zhiwei, Shi, Peihua, Chen, Zhijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728880/ https://www.ncbi.nlm.nih.gov/pubmed/31487581 http://dx.doi.org/10.1016/j.redox.2019.101309

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