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TGFβ Impairs HNF1α Functional Activity in Epithelial-to-Mesenchymal Transition Interfering With the Recruitment of CBP/p300 Acetyltransferases
The cytokine transforming growth factor β (TGFβ) plays a crucial role in the induction of both epithelial-to-mesenchymal transition (EMT) program and fibro-cirrhotic process in the liver, where it contributes also to organ inflammation following several chronic injuries. All these pathological situa...
Autores principales: | Bisceglia, Francesca, Battistelli, Cecilia, Noce, Valeria, Montaldo, Claudia, Zammataro, Agatino, Strippoli, Raffaele, Tripodi, Marco, Amicone, Laura, Marchetti, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728925/ https://www.ncbi.nlm.nih.gov/pubmed/31543815 http://dx.doi.org/10.3389/fphar.2019.00942 |
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