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Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway

BACKGROUND: m6A modification has been proved to play an important role in many biological processes. METTL3 as the main methyltransferase for methylation process has been found to be upregulated in many cancers, including CRC. Here, we investigate m6A modification and the underlying mechanism of MET...

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Detalles Bibliográficos
Autores principales:	Peng, Wen, Li, Jie, Chen, Ranran, Gu, Qiou, Yang, Peng, Qian, Wenwei, Ji, Dongjian, Wang, Qingyuan, Zhang, Zhiyuan, Tang, Junwei, Sun, Yueming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729001/ https://www.ncbi.nlm.nih.gov/pubmed/31492150 http://dx.doi.org/10.1186/s13046-019-1408-4

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