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Immune checkpoint inhibitors of PD-L1 as cancer therapeutics
Since the discovery of immune checkpoint proteins, there has been a special interest in developing antibodies that block programmed cell death 1 receptor (PD-1) and programmed cell death receptor ligand 1 (PD-L1) for a subset of cancer patients. PD-1 signaling negatively regulates T cell-mediated im...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729004/ https://www.ncbi.nlm.nih.gov/pubmed/31488176 http://dx.doi.org/10.1186/s13045-019-0779-5 |