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RhoC regulates radioresistance via crosstalk of ROCK2 with the DNA repair machinery in cervical cancer

BACKGROUND: Radioresistance remains a challenge to the successful treatment of various tumors. Intrinsic factors like alterations in signaling pathways regulate response to radiation. RhoC, which has been shown to modulate several tumor phenotypes has been investigated in this report for its role in...

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Detalles Bibliográficos
Autores principales: Pranatharthi, Annapurna, Thomas, Pavana, Udayashankar, Avinash H., Bhavani, Chandra, Suresh, Srinag Bangalore, Krishna, Sudhir, Thatte, Jayashree, Srikantia, Nirmala, Ross, Cecil R., Srivastava, Sweta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729006/
https://www.ncbi.nlm.nih.gov/pubmed/31488179
http://dx.doi.org/10.1186/s13046-019-1385-7