Optimizing gentamicin conventional and extended interval dosing in neonates using Monte Carlo simulation – a retrospective study

BACKGROUND: Although aminoglycosides are routinely used in neonates, controversy exists regarding empiric dosing regimens. The objectives were to determine gentamicin pharmacokinetics in neonates, and develop initial mg/kg dosing recommendations that optimized target peak and trough concentration at...

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Detalles Bibliográficos
Autores principales: Bergenwall, Monique, Walker, Sandra A. N., Elligsen, Marion, Iaboni, Dolores C., Findlater, Carla, Seto, Winnie, Ng, Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729057/
https://www.ncbi.nlm.nih.gov/pubmed/31492162
http://dx.doi.org/10.1186/s12887-019-1676-3

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