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Normal values of neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio among Iranian population: Results of Tabari cohort

BACKGROUND: Neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR) and platelet-lymphocyte ratio (PLR) have a prognostic value in several types of diseases such as cancers and they vary in different races. So, we aimed to evaluate the normal range of these markers among healthy people to...

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Autores principales: Moosazadeh, Mahmood, Maleki, Iradj, Alizadeh-Navaei, Reza, Kheradmand, Motahareh, Hedayatizadeh-Omran, Akbar, Shamshirian, Amir, Barzegar, Agil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729162/
https://www.ncbi.nlm.nih.gov/pubmed/31558995
http://dx.doi.org/10.22088/cjim.10.3.320
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author Moosazadeh, Mahmood
Maleki, Iradj
Alizadeh-Navaei, Reza
Kheradmand, Motahareh
Hedayatizadeh-Omran, Akbar
Shamshirian, Amir
Barzegar, Agil
author_facet Moosazadeh, Mahmood
Maleki, Iradj
Alizadeh-Navaei, Reza
Kheradmand, Motahareh
Hedayatizadeh-Omran, Akbar
Shamshirian, Amir
Barzegar, Agil
author_sort Moosazadeh, Mahmood
collection PubMed
description BACKGROUND: Neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR) and platelet-lymphocyte ratio (PLR) have a prognostic value in several types of diseases such as cancers and they vary in different races. So, we aimed to evaluate the normal range of these markers among healthy people to determine the normal value in Iranian population. METHODS: In the present study, cross-sectional data of population-based cohort study named “Tabari cohort study” was utilized. In the first phase of Tabari cohort, 10255 participants aged 35-70 years from urban and rural areas of Sari, Mazandaran, Iran entered into the study. The study included a questionnaire survey and blood collection. Blood samples were collected after 12 hours fasting from all participants during the study. Hematological indices were measured for all samples using Celltac Alpha MEK-6510 K (Tokyo, Japan). RESULTS: After sample exclusion, 2212 healthy subjects of Tabari's normal cohort population were investigated. The mean age of the samples was 47.9±9.29 years. The mean of NLR, LMR, PLR were 1.70±0.70, 11.15±3.14 and 117.05±47.73, respectively. CONCLUSION: Our investigation provides preliminary reference values for NLR, LMR, and PMR among Iranian population that can be used for disease progress in various clinical procedures.
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spelling pubmed-67291622019-09-26 Normal values of neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio among Iranian population: Results of Tabari cohort Moosazadeh, Mahmood Maleki, Iradj Alizadeh-Navaei, Reza Kheradmand, Motahareh Hedayatizadeh-Omran, Akbar Shamshirian, Amir Barzegar, Agil Caspian J Intern Med Original Article BACKGROUND: Neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR) and platelet-lymphocyte ratio (PLR) have a prognostic value in several types of diseases such as cancers and they vary in different races. So, we aimed to evaluate the normal range of these markers among healthy people to determine the normal value in Iranian population. METHODS: In the present study, cross-sectional data of population-based cohort study named “Tabari cohort study” was utilized. In the first phase of Tabari cohort, 10255 participants aged 35-70 years from urban and rural areas of Sari, Mazandaran, Iran entered into the study. The study included a questionnaire survey and blood collection. Blood samples were collected after 12 hours fasting from all participants during the study. Hematological indices were measured for all samples using Celltac Alpha MEK-6510 K (Tokyo, Japan). RESULTS: After sample exclusion, 2212 healthy subjects of Tabari's normal cohort population were investigated. The mean age of the samples was 47.9±9.29 years. The mean of NLR, LMR, PLR were 1.70±0.70, 11.15±3.14 and 117.05±47.73, respectively. CONCLUSION: Our investigation provides preliminary reference values for NLR, LMR, and PMR among Iranian population that can be used for disease progress in various clinical procedures. Babol University of Medical Sciences 2019 /pmc/articles/PMC6729162/ /pubmed/31558995 http://dx.doi.org/10.22088/cjim.10.3.320 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Moosazadeh, Mahmood
Maleki, Iradj
Alizadeh-Navaei, Reza
Kheradmand, Motahareh
Hedayatizadeh-Omran, Akbar
Shamshirian, Amir
Barzegar, Agil
Normal values of neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio among Iranian population: Results of Tabari cohort
title Normal values of neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio among Iranian population: Results of Tabari cohort
title_full Normal values of neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio among Iranian population: Results of Tabari cohort
title_fullStr Normal values of neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio among Iranian population: Results of Tabari cohort
title_full_unstemmed Normal values of neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio among Iranian population: Results of Tabari cohort
title_short Normal values of neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio among Iranian population: Results of Tabari cohort
title_sort normal values of neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio among iranian population: results of tabari cohort
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729162/
https://www.ncbi.nlm.nih.gov/pubmed/31558995
http://dx.doi.org/10.22088/cjim.10.3.320
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