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Plummer-Vinson Syndrome and Heart Failure: An Unusual Association in an African American Woman
Patient: Female, 48 Final Diagnosis: Plummer-Vinson syndrome Symptoms: Chest pain • fatigue • palpitation Medication: — Clinical Procedure: Esophagogastroduodenoscopy (EGD) • colonoscopy Specialty: General and Internal Medicine OBJECTIVE: Rare disease BACKGROUND: Plummer-Vinson syndrome (PVS) is a r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730079/ https://www.ncbi.nlm.nih.gov/pubmed/31451679 http://dx.doi.org/10.12659/AJCR.916823 |
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author | Field, Zachary Russin, Michelle Kropf, Jacqueline Olivier, Maxim Ge, Li Galili, Yehuda Carlan, Steve J. |
author_facet | Field, Zachary Russin, Michelle Kropf, Jacqueline Olivier, Maxim Ge, Li Galili, Yehuda Carlan, Steve J. |
author_sort | Field, Zachary |
collection | PubMed |
description | Patient: Female, 48 Final Diagnosis: Plummer-Vinson syndrome Symptoms: Chest pain • fatigue • palpitation Medication: — Clinical Procedure: Esophagogastroduodenoscopy (EGD) • colonoscopy Specialty: General and Internal Medicine OBJECTIVE: Rare disease BACKGROUND: Plummer-Vinson syndrome (PVS) is a rare disorder composed of the triad of dysphagia, iron-deficiency anemia (IDA), and esophageal webs. It is most prevalent in middle-aged white women, and the dysphagia often improves when the anemia is treated. It is well established that chronic hypertension can lead to congestive heart failure (CHF). While IDA is frequently found concomitantly with CHF, there have been no reported cases of new-onset CHF with anemia presenting as PVS. CASE REPORT: We present the case of a 48-year-old African American woman with symptomatic anemia and new-onset congestive heart failure secondary to hypertension, who presented with the classic symptoms of PVS. CONCLUSIONS: CHF with accompanying IDA may be an independent risk factor for the development of PVS. At the very least, there is an association between CHF-induced IDA and PVS. Patients presenting with CHF with symptoms of dysphagia should be considered at risk for the syndrome, and endoscopy may be warranted. Treatment for PVS includes iron replacement, and in some cases requires mechanical dilation. |
format | Online Article Text |
id | pubmed-6730079 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-67300792019-09-19 Plummer-Vinson Syndrome and Heart Failure: An Unusual Association in an African American Woman Field, Zachary Russin, Michelle Kropf, Jacqueline Olivier, Maxim Ge, Li Galili, Yehuda Carlan, Steve J. Am J Case Rep Articles Patient: Female, 48 Final Diagnosis: Plummer-Vinson syndrome Symptoms: Chest pain • fatigue • palpitation Medication: — Clinical Procedure: Esophagogastroduodenoscopy (EGD) • colonoscopy Specialty: General and Internal Medicine OBJECTIVE: Rare disease BACKGROUND: Plummer-Vinson syndrome (PVS) is a rare disorder composed of the triad of dysphagia, iron-deficiency anemia (IDA), and esophageal webs. It is most prevalent in middle-aged white women, and the dysphagia often improves when the anemia is treated. It is well established that chronic hypertension can lead to congestive heart failure (CHF). While IDA is frequently found concomitantly with CHF, there have been no reported cases of new-onset CHF with anemia presenting as PVS. CASE REPORT: We present the case of a 48-year-old African American woman with symptomatic anemia and new-onset congestive heart failure secondary to hypertension, who presented with the classic symptoms of PVS. CONCLUSIONS: CHF with accompanying IDA may be an independent risk factor for the development of PVS. At the very least, there is an association between CHF-induced IDA and PVS. Patients presenting with CHF with symptoms of dysphagia should be considered at risk for the syndrome, and endoscopy may be warranted. Treatment for PVS includes iron replacement, and in some cases requires mechanical dilation. International Scientific Literature, Inc. 2019-08-27 /pmc/articles/PMC6730079/ /pubmed/31451679 http://dx.doi.org/10.12659/AJCR.916823 Text en © Am J Case Rep, 2019 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) ) |
spellingShingle | Articles Field, Zachary Russin, Michelle Kropf, Jacqueline Olivier, Maxim Ge, Li Galili, Yehuda Carlan, Steve J. Plummer-Vinson Syndrome and Heart Failure: An Unusual Association in an African American Woman |
title | Plummer-Vinson Syndrome and Heart Failure: An Unusual Association in an African American Woman |
title_full | Plummer-Vinson Syndrome and Heart Failure: An Unusual Association in an African American Woman |
title_fullStr | Plummer-Vinson Syndrome and Heart Failure: An Unusual Association in an African American Woman |
title_full_unstemmed | Plummer-Vinson Syndrome and Heart Failure: An Unusual Association in an African American Woman |
title_short | Plummer-Vinson Syndrome and Heart Failure: An Unusual Association in an African American Woman |
title_sort | plummer-vinson syndrome and heart failure: an unusual association in an african american woman |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730079/ https://www.ncbi.nlm.nih.gov/pubmed/31451679 http://dx.doi.org/10.12659/AJCR.916823 |
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