Quantification of T-Cell and B-Cell Replication History in Aging, Immunodeficiency, and Newborn Screening

Quantification of T-cell receptor excision circles (TRECs) has impacted on human T-cell research, but interpretations on T-cell replication have been limited due to the lack of a genomic coding joint. We here overcome this limitation with multiplex TRG rearrangement quantification (detecting ~0.98 a...

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Detalles Bibliográficos
Autores principales: Verstegen, Ruud H. J., Aui, Pei M., Watson, Eliza, De Jong, Samuel, Bartol, Sophinus J. W., Bosco, Julian J., Cameron, Paul U., Stirling, Robert G., de Vries, Esther, van Dongen, Jacques J. M., van Zelm, Menno C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730487/
https://www.ncbi.nlm.nih.gov/pubmed/31543882
http://dx.doi.org/10.3389/fimmu.2019.02084

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