Regulator of G protein signaling 12 enhances osteoclastogenesis by suppressing Nrf2-dependent antioxidant proteins to promote the generation of reactive oxygen species

Regulators of G-protein Signaling are a conserved family of proteins required in various biological processes including cell differentiation. We previously demonstrated that Rgs12 is essential for osteoclast differentiation and its deletion in vivo protected mice against pathological bone loss. To c...

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Detalles Bibliográficos
Autores principales: Ng, Andrew Ying Hui, Li, Ziqing, Jones, Megan M, Yang, Shuting, Li, Chunyi, Fu, Chuanyun, Tu, Chengjian, Oursler, Merry Jo, Qu, Jun, Yang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731062/
https://www.ncbi.nlm.nih.gov/pubmed/31490121
http://dx.doi.org/10.7554/eLife.42951

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