Distinctive mechanisms underlie the loss of SMARCB1 protein expression in renal medullary carcinoma: morphologic and molecular analysis of 20 cases

Renal medullary carcinoma is a rare but highly aggressive type of renal cancer occurring in patients with sickle cell trait or rarely with other hemoglobinopathies. Loss of SMARCB1 protein expression, a core subunit of the switch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complex, has eme...

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Detalles Bibliográficos
Autores principales: Jia, Liwei, Carlo, Maria I., Khan, Hina, Nanjangud, Gouri J., Rana, Satshil, Cimera, Robert, Zhang, Yanming, Hakimi, A. Ari, Verma, Amit K., Al-Ahmadie, Hikmat A., Fine, Samson W., Gopalan, Anuradha, Sirintrapun, S. Joseph, Tickoo, Satish K., Reuter, Victor E., Gartrell, Benjamin A., Chen, Ying-Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731129/
https://www.ncbi.nlm.nih.gov/pubmed/30980040
http://dx.doi.org/10.1038/s41379-019-0273-1

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