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Systemic delivery and SPECT/CT in vivo imaging of (125)I-labelled oncolytic adenoviral mutants in models of pancreatic cancer

Early phase clinical trials have demonstrated good therapeutic index for oncolytic adenoviruses in patients with solid tumours when administered intratumorally, resulting in local tumour elimination. Entrapment and binding of adenovirus to erythrocytes, blood factors, and neutralising antibodies hav...

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Detalles Bibliográficos
Autores principales:	Stella Man, Y. K., Foster, Julie, Carapuça, Elisabete, Davies, James A., Parker, Alan L., Sosabowski, Jane, Halldén, Gunnel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731255/ https://www.ncbi.nlm.nih.gov/pubmed/31492884 http://dx.doi.org/10.1038/s41598-019-49150-9

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