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A second open reading frame in human enterovirus determines viral replication in intestinal epithelial cells

Human enteroviruses (HEVs) of the family Picornaviridae, which comprises non-enveloped RNA viruses, are ubiquitous worldwide. The majority of EV proteins are derived from viral polyproteins encoded by a single open reading frame (ORF). Here, we characterize a second ORF in HEVs that is crucial for v...

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Detalles Bibliográficos
Autores principales:	Guo, Haoran, Li, Yan, Liu, Guanchen, Jiang, Yunhe, Shen, Siyu, Bi, Ran, Huang, Honglan, Cheng, Tong, Wang, Chunxi, Wei, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731315/ https://www.ncbi.nlm.nih.gov/pubmed/31492846 http://dx.doi.org/10.1038/s41467-019-12040-9

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