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In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation
Homologous recombination (HR) uses a homologous template to accurately repair DNA double-strand breaks and stalled replication forks to maintain genome stability. During homology search, Rad51 nucleoprotein filaments probe and interact with dsDNA, forming the synaptic complex that is stabilized on a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731316/ https://www.ncbi.nlm.nih.gov/pubmed/31492866 http://dx.doi.org/10.1038/s41467-019-12082-z |