Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing

Nucleosomes containing the histone H3 variant CENP-A are the epigenetic mark of centromeres, the kinetochore assembly sites required for chromosome segregation. HJURP is the CENP-A chaperone, which associates with Mis18α, Mis18β, and M18BP1 to target centromeres and deposit new CENP-A. How these pro...

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Detalles Bibliográficos
Autores principales: Pan, Dongqing, Walstein, Kai, Take, Annika, Bier, David, Kaiser, Nadine, Musacchio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731319/
https://www.ncbi.nlm.nih.gov/pubmed/31492860
http://dx.doi.org/10.1038/s41467-019-12019-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731319/
https://www.ncbi.nlm.nih.gov/pubmed/31492860
http://dx.doi.org/10.1038/s41467-019-12019-6

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