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Experimentally-driven mathematical modeling to improve combination targeted and cytotoxic therapy for HER2+ breast cancer

The goal of this study is to experimentally and computationally investigate combination trastuzumab-paclitaxel therapies and identify potential synergistic effects due to sequencing of the therapies with in vitro imaging and mathematical modeling. Longitudinal alterations in cell confluence are repo...

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Detalles Bibliográficos
Autores principales:	Jarrett, Angela M., Shah, Alay, Bloom, Meghan J., McKenna, Matthew T., Hormuth, David A., Yankeelov, Thomas E., Sorace, Anna G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731321/ https://www.ncbi.nlm.nih.gov/pubmed/31492947 http://dx.doi.org/10.1038/s41598-019-49073-5

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