Cargando…

Wnt signaling regulates trans-differentiation of stem cell like type 2 alveolar epithelial cells to type 1 epithelial cells

BACKGROUND: Type 2 alveolar epithelial cells (AT2s) behave as stem cells and show clonal proliferation upon alveolar injury followed by trans-differentiation (TD) into Type 1 alveolar epithelial cells (AT1s). In the present study we identified signaling pathways involved in the physiological AT2-to-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abdelwahab, Elhusseiny Mohamed Mahmud, Rapp, Judit, Feller, Diana, Csongei, Veronika, Pal, Szilard, Bartis, Domokos, Thickett, David R., Pongracz, Judit Erzsebet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731587/ https://www.ncbi.nlm.nih.gov/pubmed/31492143 http://dx.doi.org/10.1186/s12931-019-1176-x

Ejemplares similares

Multiple suppression pathways of canonical Wnt signalling control thymic epithelial senescence
por: Varecza, Zoltan, et al.
Publicado: (2011)

Alteration in the Wnt microenvironment directly regulates molecular events leading to pulmonary senescence
por: Kovacs, Tamas, et al.
Publicado: (2014)

KRAS and EGFR Mutations Differentially Alter ABC Drug Transporter Expression in Cisplatin-Resistant Non-Small Cell Lung Cancer
por: Jaromi, Luca, et al.
Publicado: (2021)

Down-Regulation of Canonical and Up-Regulation of Non-Canonical Wnt Signalling in the Carcinogenic Process of Squamous Cell Lung Carcinoma
por: Bartis, Domokos, et al.
Publicado: (2013)

Wnt4 and LAP2alpha as Pacemakers of Thymic Epithelial Senescence
por: Kvell, Krisztian, et al.
Publicado: (2010)

Feasibility study of in vitro drug sensitivity assay of advanced non-small cell lung adenocarcinomas
por: Papp, Emoke, et al.
Publicado: (2020)

miRNAs as Predictors of Barrier Integrity
por: Bovari-Biri, Judit, et al.
Publicado: (2023)

Prdx5 in the Regulation of Tuberous Sclerosis Complex Mutation-Induced Signaling Mechanisms
por: Bovari-Biri, Judit, et al.
Publicado: (2023)

Cigarette Smoke-Induced Pulmonary Inflammation Becomes Systemic by Circulating Extracellular Vesicles Containing Wnt5a and Inflammatory Cytokines
por: Feller, Diana, et al.
Publicado: (2018)

Hyperoxia inhibits alveolar epithelial repair by inhibiting the transdifferentiation of alveolar epithelial type II cells into type I cells
por: McKechnie, S, et al.
Publicado: (2008)

Cisplatin treatment induced interleukin 6 and 8 production alters lung adenocarcinoma cell migration in an oncogenic mutation dependent manner
por: Kiss, Edit, et al.
Publicado: (2020)

Activated p53 in the anti-apoptotic milieu of tuberous sclerosis gene mutation induced diseases leads to cell death if thioredoxin reductase is inhibited
por: Abdelwahab, ElHusseiny M. M., et al.
Publicado: (2021)

Role of CD248 as a potential severity marker in idiopathic pulmonary fibrosis
por: Bartis, Domokos, et al.
Publicado: (2016)

Normalization of Enzyme Expression and Activity Regulating Vitamin A Metabolism Increases RAR-Beta Expression and Reduces Cellular Migration and Proliferation in Diseases Caused by Tuberous Sclerosis Gene Mutations
por: Abdelwahab, Elhusseiny Mohamed Mahmoud, et al.
Publicado: (2021)

Alveolar epithelial type II cell: defender of the alveolus revisited
por: Fehrenbach, Heinz
Publicado: (2001)

Human alveolar epithelial type II cells in primary culture
por: Mao, Pu, et al.
Publicado: (2015)

Culture of human alveolar epithelial type II cells by sprouting
por: Khan, Petra, et al.
Publicado: (2018)

WNT signaling – lung cancer is no exception
por: Rapp, Judit, et al.
Publicado: (2017)

Lipoxin A(4) promotes lung epithelial repair whilst inhibiting fibroblast proliferation
por: Zheng, Shengxing, et al.
Publicado: (2016)

Potential contribution of alveolar epithelial type I cells to pulmonary fibrosis
por: Kasper, Michael, et al.
Publicado: (2017)

Alveolar Type 2 Epithelial Cell Organoids: Focus on Culture Methods
por: Jain, Krishan Gopal, et al.
Publicado: (2023)

Alveolar Epithelial Type II Cells Activate Alveolar Macrophages and Mitigate P. Aeruginosa Infection
por: Kannan, Shibichakravarthy, et al.
Publicado: (2009)

Proteomic and ultrastructural analysis of Clara cell and type II alveolar epithelial cell-type lung cancer cells
por: Hou, Wen-Li, et al.
Publicado: (2020)

Generation of human alveolar epithelial type I cells from pluripotent stem cells
por: Burgess, Claire L, et al.
Publicado: (2023)

Transcriptional Profile of Mycobacterium tuberculosis Replicating in Type II Alveolar Epithelial Cells
por: Ryndak, Michelle B., et al.
Publicado: (2015)

Klebsiella pneumoniae infection inhibits autophagy by alveolar type II epithelial cells
por: Shi, Zhiyun, et al.
Publicado: (2020)

microRNA Expression Profile of Purified Alveolar Epithelial Type II Cells
por: Dehmel, Stefan, et al.
Publicado: (2022)

Alveolar type 2 epithelial cell senescence and radiation-induced pulmonary fibrosis
por: Zhou, Shenghui, et al.
Publicado: (2022)

Alveolar Macrophages Prevent Lethal Influenza Pneumonia By Inhibiting Infection Of Type-1 Alveolar Epithelial Cells
por: Cardani, Amber, et al.
Publicado: (2017)

Continuous purification and culture of rat type 1 and type 2 alveolar epithelial cells by magnetic cell sorting
por: Liu, Di, et al.
Publicado: (2022)

miR-375 regulates rat alveolar epithelial cell trans-differentiation by inhibiting Wnt/β-catenin pathway
por: Wang, Yang, et al.
Publicado: (2013)

The Impact of Fermented Wheat Germ Extract on Porcine Epithelial Cell Line Exposed to Deoxynivalenol and T-2 Mycotoxins
por: Pomothy, Judit Mercédesz, et al.
Publicado: (2020)

Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth
por: Gschwend, Julia, et al.
Publicado: (2021)

Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis
por: Goldmann, Torsten, et al.
Publicado: (2018)

Exposure of human intestinal epithelial cells and primary human hepatocytes to trypsin-like serine protease inhibitors with potential antiviral effect
por: Pászti-Gere, Erzsébet, et al.
Publicado: (2021)

Ciclesonide uptake and metabolism in human alveolar type II epithelial cells (A549)
por: Nonaka, Takashi, et al.
Publicado: (2007)

State-dependent inactivation of K+ currents in rat type II alveolar epithelial cells
Publicado: (1990)

Isolation of alveolar epithelial type II progenitor cells from adult human lungs
por: Fujino, Naoya, et al.
Publicado: (2011)

Potential Contribution of Type I Alveolar Epithelial Cells to Chronic Neonatal Lung Disease
por: Rozycki, Henry J.
Publicado: (2014)

Double impact of cigarette smoke and mechanical ventilation on the alveolar epithelial type II cell
por: Hirsch, Jan, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6ak6vn9ouk05iu20e200usdasg