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Parkinson’s disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclein
Many neurodegenerative diseases are characterized by the accumulation of abnormal protein aggregates in the brain. In Parkinson’s disease (PD), α-synuclein (α-syn) forms such aggregates called Lewy bodies (LBs). Recently, it has been reported that aggregates of α-syn with a cross-β structure are cap...
Autores principales: | Araki, Katsuya, Yagi, Naoto, Aoyama, Koki, Choong, Chi-Jing, Hayakawa, Hideki, Fujimura, Harutoshi, Nagai, Yoshitaka, Goto, Yuji, Mochizuki, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731630/ https://www.ncbi.nlm.nih.gov/pubmed/31427526 http://dx.doi.org/10.1073/pnas.1906124116 |
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