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Sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales
Population genetics has been successful at identifying the relationships between human groups and their interconnected histories. However, the link between genetic demography inferred at large scales and the individual human behaviours that ultimately generate that demography is not always clear. Wh...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731738/ https://www.ncbi.nlm.nih.gov/pubmed/31598251 http://dx.doi.org/10.1098/rsos.190733 |
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author | Chung, Ning Ning Jacobs, Guy S. Sudoyo, Herawati Malik, Safarina G. Chew, Lock Yue Lansing, J. Stephen Cox, Murray P. |
author_facet | Chung, Ning Ning Jacobs, Guy S. Sudoyo, Herawati Malik, Safarina G. Chew, Lock Yue Lansing, J. Stephen Cox, Murray P. |
author_sort | Chung, Ning Ning |
collection | PubMed |
description | Population genetics has been successful at identifying the relationships between human groups and their interconnected histories. However, the link between genetic demography inferred at large scales and the individual human behaviours that ultimately generate that demography is not always clear. While anthropological and historical context are routinely presented as adjuncts in population genetic studies to help describe the past, determining how underlying patterns of human sociocultural behaviour impact genetics still remains challenging. Here, we analyse patterns of genetic variation in village-scale samples from two islands in eastern Indonesia, patrilocal Sumba and a matrilocal region of Timor. Adopting a ‘process modelling’ approach, we iteratively explore combinations of structurally different models as a thinking tool. We find interconnected socio-genetic interactions involving sex-biased migration, lineage-focused founder effects, and on Sumba, heritable social dominance. Strikingly, founder ideology, a cultural model derived from anthropological and archaeological studies at larger regional scales, has both its origins and impact at the scale of villages. Process modelling lets us explore these complex interactions, first by circumventing the complexity of formal inference when studying large datasets with many interacting parts, and then by explicitly testing complex anthropological hypotheses about sociocultural behaviour from a more familiar population genetic standpoint. |
format | Online Article Text |
id | pubmed-6731738 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Royal Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-67317382019-10-09 Sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales Chung, Ning Ning Jacobs, Guy S. Sudoyo, Herawati Malik, Safarina G. Chew, Lock Yue Lansing, J. Stephen Cox, Murray P. R Soc Open Sci Genetics and Genomics Population genetics has been successful at identifying the relationships between human groups and their interconnected histories. However, the link between genetic demography inferred at large scales and the individual human behaviours that ultimately generate that demography is not always clear. While anthropological and historical context are routinely presented as adjuncts in population genetic studies to help describe the past, determining how underlying patterns of human sociocultural behaviour impact genetics still remains challenging. Here, we analyse patterns of genetic variation in village-scale samples from two islands in eastern Indonesia, patrilocal Sumba and a matrilocal region of Timor. Adopting a ‘process modelling’ approach, we iteratively explore combinations of structurally different models as a thinking tool. We find interconnected socio-genetic interactions involving sex-biased migration, lineage-focused founder effects, and on Sumba, heritable social dominance. Strikingly, founder ideology, a cultural model derived from anthropological and archaeological studies at larger regional scales, has both its origins and impact at the scale of villages. Process modelling lets us explore these complex interactions, first by circumventing the complexity of formal inference when studying large datasets with many interacting parts, and then by explicitly testing complex anthropological hypotheses about sociocultural behaviour from a more familiar population genetic standpoint. The Royal Society 2019-08-28 /pmc/articles/PMC6731738/ /pubmed/31598251 http://dx.doi.org/10.1098/rsos.190733 Text en © 2019 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited. |
spellingShingle | Genetics and Genomics Chung, Ning Ning Jacobs, Guy S. Sudoyo, Herawati Malik, Safarina G. Chew, Lock Yue Lansing, J. Stephen Cox, Murray P. Sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales |
title | Sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales |
title_full | Sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales |
title_fullStr | Sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales |
title_full_unstemmed | Sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales |
title_short | Sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales |
title_sort | sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales |
topic | Genetics and Genomics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731738/ https://www.ncbi.nlm.nih.gov/pubmed/31598251 http://dx.doi.org/10.1098/rsos.190733 |
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