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FOXN3 hyperglycemic risk allele and insulin sensitivity in humans

OBJECTIVE: The rs8004664 variation within the FOXN3 gene is significantly and independently associated with fasting blood glucose in humans. We have previously shown that the hyperglycemia risk allele (A) increases FOXN3 expression in primary human hepatocytes; over-expression of human FOXN3 in zebr...

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Detalles Bibliográficos
Autores principales:	Erickson, Melissa L, Karanth, Santhosh, Ravussin, Eric, Schlegel, Amnon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731827/ https://www.ncbi.nlm.nih.gov/pubmed/31543974 http://dx.doi.org/10.1136/bmjdrc-2019-000688

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