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Distinct Molecular Trajectories Converge to Induce Naive Pluripotency

Understanding how cell identity transitions occur and whether there are multiple paths between the same beginning and end states are questions of wide interest. Here we show that acquisition of naive pluripotency can follow transcriptionally and mechanistically distinct routes. Starting from post-im...

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Detalles Bibliográficos
Autores principales: Stuart, Hannah T., Stirparo, Giuliano G., Lohoff, Tim, Bates, Lawrence E., Kinoshita, Masaki, Lim, Chee Y., Sousa, Elsa J., Maskalenka, Katsiaryna, Radzisheuskaya, Aliaksandra, Malcolm, Andrew A., Alves, Mariana R.P., Lloyd, Rebecca L., Nestorowa, Sonia, Humphreys, Peter, Mansfield, William, Reik, Wolf, Bertone, Paul, Nichols, Jennifer, Göttgens, Berthold, Silva, José C.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731995/
https://www.ncbi.nlm.nih.gov/pubmed/31422912
http://dx.doi.org/10.1016/j.stem.2019.07.009