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Percutaneous transcatheter closure of high-risk patent foramen ovale in the elderly
The efficacy of percutaneous transcatheter closure for preventing recurrent cerebrovascular events in elderly patients with high-risk patent foramen ovale (PFO) remains unclear, whereas in young patients, it has been shown to effectively prevent the recurrence of embolic stroke. The aim of this stud...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732153/ https://www.ncbi.nlm.nih.gov/pubmed/30868214 http://dx.doi.org/10.1007/s00380-019-01379-0 |
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author | Takafuji, Hiroya Hosokawa, Shinobu Ogura, Riyo Hiasa, Yoshikazu |
author_facet | Takafuji, Hiroya Hosokawa, Shinobu Ogura, Riyo Hiasa, Yoshikazu |
author_sort | Takafuji, Hiroya |
collection | PubMed |
description | The efficacy of percutaneous transcatheter closure for preventing recurrent cerebrovascular events in elderly patients with high-risk patent foramen ovale (PFO) remains unclear, whereas in young patients, it has been shown to effectively prevent the recurrence of embolic stroke. The aim of this study was to investigate the safety and efficacy of percutaneous PFO closure in elderly patients with high-risk PFO. Between September 2012 and October 2018, 14 patients ≥ 60 years old with high-risk PFO underwent percutaneous closure to prevent recurrence of cerebrovascular events. The primary end point was recurrence of cerebrovascular events after closure in elderly patients with high-risk PFO, and the secondary end points were occurrence of device-related complications, cerebral hemorrhage, and new-onset atrial fibrillation (AF). The mean patient age and number of cerebrovascular events before closure were 75.2 ± 6.5 years and 1.7 ± 0.7, respectively. All procedures were successfully performed under general anesthesia by transesophageal echocardiography and using a 25-mm Amplatzer Cribriform device. No procedure-related complications occurred. Patients were followed up for a mean 2.6 ± 1.8 years. No patients experienced device-related complications or recurrent cerebrovascular events. However, one patient had AF-related device closure complications at 1 month postoperatively. In addition, other patient had a cerebral hemorrhage with unknown relationship to PFO closure 3 years postoperatively. Percutaneous closure of high-risk PFO in elderly patients may be as effective and safe as in younger patients. It is crucial to evaluate PFO morphology regardless of age in cases of paradoxical embolism. |
format | Online Article Text |
id | pubmed-6732153 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Springer Japan |
record_format | MEDLINE/PubMed |
spelling | pubmed-67321532019-09-20 Percutaneous transcatheter closure of high-risk patent foramen ovale in the elderly Takafuji, Hiroya Hosokawa, Shinobu Ogura, Riyo Hiasa, Yoshikazu Heart Vessels Original Article The efficacy of percutaneous transcatheter closure for preventing recurrent cerebrovascular events in elderly patients with high-risk patent foramen ovale (PFO) remains unclear, whereas in young patients, it has been shown to effectively prevent the recurrence of embolic stroke. The aim of this study was to investigate the safety and efficacy of percutaneous PFO closure in elderly patients with high-risk PFO. Between September 2012 and October 2018, 14 patients ≥ 60 years old with high-risk PFO underwent percutaneous closure to prevent recurrence of cerebrovascular events. The primary end point was recurrence of cerebrovascular events after closure in elderly patients with high-risk PFO, and the secondary end points were occurrence of device-related complications, cerebral hemorrhage, and new-onset atrial fibrillation (AF). The mean patient age and number of cerebrovascular events before closure were 75.2 ± 6.5 years and 1.7 ± 0.7, respectively. All procedures were successfully performed under general anesthesia by transesophageal echocardiography and using a 25-mm Amplatzer Cribriform device. No procedure-related complications occurred. Patients were followed up for a mean 2.6 ± 1.8 years. No patients experienced device-related complications or recurrent cerebrovascular events. However, one patient had AF-related device closure complications at 1 month postoperatively. In addition, other patient had a cerebral hemorrhage with unknown relationship to PFO closure 3 years postoperatively. Percutaneous closure of high-risk PFO in elderly patients may be as effective and safe as in younger patients. It is crucial to evaluate PFO morphology regardless of age in cases of paradoxical embolism. Springer Japan 2019-03-13 2019 /pmc/articles/PMC6732153/ /pubmed/30868214 http://dx.doi.org/10.1007/s00380-019-01379-0 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Article Takafuji, Hiroya Hosokawa, Shinobu Ogura, Riyo Hiasa, Yoshikazu Percutaneous transcatheter closure of high-risk patent foramen ovale in the elderly |
title | Percutaneous transcatheter closure of high-risk patent foramen ovale in the elderly |
title_full | Percutaneous transcatheter closure of high-risk patent foramen ovale in the elderly |
title_fullStr | Percutaneous transcatheter closure of high-risk patent foramen ovale in the elderly |
title_full_unstemmed | Percutaneous transcatheter closure of high-risk patent foramen ovale in the elderly |
title_short | Percutaneous transcatheter closure of high-risk patent foramen ovale in the elderly |
title_sort | percutaneous transcatheter closure of high-risk patent foramen ovale in the elderly |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732153/ https://www.ncbi.nlm.nih.gov/pubmed/30868214 http://dx.doi.org/10.1007/s00380-019-01379-0 |
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