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Influence of CYP2D6, CYP3A5, ABCB1, APOE polymorphisms and nongenetic factors on donepezil treatment in patients with Alzheimer’s disease and vascular dementia

PURPOSE: This study aims to evaluate the influence of genetic polymorphisms of CYP2D6, CYP3A5, ABCB1, and APOE genes and nongenetic factors on steady-state plasma concentrations (Cpss) of donepezil and therapeutic outcomes in Thai patients with Alzheimer’s disease (AD) and vascular dementia (VAD). P...

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Detalles Bibliográficos
Autores principales:	Yaowaluk, Thitipon, Senanarong, Vorapun, Limwongse, Chanin, Boonprasert, Rasda, Kijsanayotin, Pornpimol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732559/ https://www.ncbi.nlm.nih.gov/pubmed/31564952 http://dx.doi.org/10.2147/PGPM.S211259

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