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Therapeutic potential of BLT1 antagonist for COPD: involvement of inducing autophagy and ameliorating inflammation

PURPOSE: Leukotriene B4 (LTB4) is a major pro-inflammatory mediator that leads to the persistence of chronic inflammation in chronic obstructive pulmonary disease (COPD). The purpose of this study was to evaluate therapeutic potential of BLT1 antagonist for cigarette smoke (CS)-induced COPD and to e...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Huang, Jingwen, Dong, Ran, Feng, Yun, Zhou, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732561/
https://www.ncbi.nlm.nih.gov/pubmed/31564828
http://dx.doi.org/10.2147/DDDT.S215433