Pretargeted Nuclear Imaging and Radioimmunotherapy Based on the Inverse Electron-Demand Diels–Alder Reaction and Key Factors in the Pretargeted Synthetic Design

The exceptional speed and biorthogonality of the inverse electron-demand Diels–Alder (IEDDA) click chemistry between 1,2,4,5-tetrazines and strained alkene dienophiles have made it promising in the realm of pretargeted imaging and therapy. During the past 10 years, the IEDDA-pretargeted strategies h...

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Detalles Bibliográficos
Autores principales: Qiu, Lin, Mao, Wujian, Yin, Hongyan, Tan, Hui, Cheng, Dengfeng, Shi, Hongcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732628/
https://www.ncbi.nlm.nih.gov/pubmed/31531006
http://dx.doi.org/10.1155/2019/9182476

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