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Solitary fibrous tumor of the kidney: A case report

INTRODUCTION: Solitary fibrous tumor (SFT) is rare, representing 2% of all soft tissue tumors and is usually described in the thoracic cavity. Only 105 cases of renal SFT have been reported. CASE PRESENTATION: A 55-year-old men with lower urinary tract symptoms, had a routine renal ultrasound which...

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Autores principales: Zaghbib, Selim, Chakroun, Marouene, Essid, Mohamed Ali, Saadi, Ahmed, Bouzouita, Abderrazak, Derouiche, Amine, Slama, Mohamed Riadh Ben, Ayed, Haroun, Chebil, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732730/
https://www.ncbi.nlm.nih.gov/pubmed/31494455
http://dx.doi.org/10.1016/j.ijscr.2019.08.004
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author Zaghbib, Selim
Chakroun, Marouene
Essid, Mohamed Ali
Saadi, Ahmed
Bouzouita, Abderrazak
Derouiche, Amine
Slama, Mohamed Riadh Ben
Ayed, Haroun
Chebil, Mohamed
author_facet Zaghbib, Selim
Chakroun, Marouene
Essid, Mohamed Ali
Saadi, Ahmed
Bouzouita, Abderrazak
Derouiche, Amine
Slama, Mohamed Riadh Ben
Ayed, Haroun
Chebil, Mohamed
author_sort Zaghbib, Selim
collection PubMed
description INTRODUCTION: Solitary fibrous tumor (SFT) is rare, representing 2% of all soft tissue tumors and is usually described in the thoracic cavity. Only 105 cases of renal SFT have been reported. CASE PRESENTATION: A 55-year-old men with lower urinary tract symptoms, had a routine renal ultrasound which showed a cortical mass of the left kidney measuring 36 × 23 × 39 mm, with peripheral enhancement, and a central fluid collection on CT. On MRI, it was iso-intense to the kidney in T1 and hyper-intense with restricted diffusion in T2 images. The diagnosis of renal cell cancer was likely and an open partial nephrectomy was performed. Microscopic examination showed a mesenchymal neoplasm with long spindle cell and Immunohistochemical staining positive for CD34 and Bcl-2 confirming the diagnosis of SFT. There was no evidence of tumor recurrence or metastasis nine months after discharge. DISCUSSION: Up to now, only 105 cases of occurring renal SFT have been reported. SFTs are usually asymptomatic when they have a small size, that’s why the diagnosis is often delayed. Blood tests do not have any diagnostic value. Imaging features are not specific for the diagnosis of SFT which are diagnosed as renal cell carcinoma and treated as such. Typical immunohistochemical characteristic is a high positivity for CD34. As SFT has a malignant potential, careful follow-up is mandatory,searching for local recurrence or metastasis which was reported in few cases. CONLUSION: SFTs are indolent tumors and are usually diagnosed as renal cell carcinomas preoperatively and the final diagnosis is always based on immunohistochemical study.
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spelling pubmed-67327302019-09-12 Solitary fibrous tumor of the kidney: A case report Zaghbib, Selim Chakroun, Marouene Essid, Mohamed Ali Saadi, Ahmed Bouzouita, Abderrazak Derouiche, Amine Slama, Mohamed Riadh Ben Ayed, Haroun Chebil, Mohamed Int J Surg Case Rep Article INTRODUCTION: Solitary fibrous tumor (SFT) is rare, representing 2% of all soft tissue tumors and is usually described in the thoracic cavity. Only 105 cases of renal SFT have been reported. CASE PRESENTATION: A 55-year-old men with lower urinary tract symptoms, had a routine renal ultrasound which showed a cortical mass of the left kidney measuring 36 × 23 × 39 mm, with peripheral enhancement, and a central fluid collection on CT. On MRI, it was iso-intense to the kidney in T1 and hyper-intense with restricted diffusion in T2 images. The diagnosis of renal cell cancer was likely and an open partial nephrectomy was performed. Microscopic examination showed a mesenchymal neoplasm with long spindle cell and Immunohistochemical staining positive for CD34 and Bcl-2 confirming the diagnosis of SFT. There was no evidence of tumor recurrence or metastasis nine months after discharge. DISCUSSION: Up to now, only 105 cases of occurring renal SFT have been reported. SFTs are usually asymptomatic when they have a small size, that’s why the diagnosis is often delayed. Blood tests do not have any diagnostic value. Imaging features are not specific for the diagnosis of SFT which are diagnosed as renal cell carcinoma and treated as such. Typical immunohistochemical characteristic is a high positivity for CD34. As SFT has a malignant potential, careful follow-up is mandatory,searching for local recurrence or metastasis which was reported in few cases. CONLUSION: SFTs are indolent tumors and are usually diagnosed as renal cell carcinomas preoperatively and the final diagnosis is always based on immunohistochemical study. Elsevier 2019-08-20 /pmc/articles/PMC6732730/ /pubmed/31494455 http://dx.doi.org/10.1016/j.ijscr.2019.08.004 Text en © 2019 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zaghbib, Selim
Chakroun, Marouene
Essid, Mohamed Ali
Saadi, Ahmed
Bouzouita, Abderrazak
Derouiche, Amine
Slama, Mohamed Riadh Ben
Ayed, Haroun
Chebil, Mohamed
Solitary fibrous tumor of the kidney: A case report
title Solitary fibrous tumor of the kidney: A case report
title_full Solitary fibrous tumor of the kidney: A case report
title_fullStr Solitary fibrous tumor of the kidney: A case report
title_full_unstemmed Solitary fibrous tumor of the kidney: A case report
title_short Solitary fibrous tumor of the kidney: A case report
title_sort solitary fibrous tumor of the kidney: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732730/
https://www.ncbi.nlm.nih.gov/pubmed/31494455
http://dx.doi.org/10.1016/j.ijscr.2019.08.004
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