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Transurethral resection of prostate for acute urinary retention is linked to shorter survival in younger men

It is largely unknown whether lower urinary tract symptoms (LUTS) or acute retention of urine (AROU) is linked to shorter life expectancy in men. We conducted a multicenter, retrospective database analysis of patients undergoing transurethral resection of prostate (TURP) to study their relationships...

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Autores principales: Teoh, Jeremy Yuen-Chun, Chan, Chi-Kwok, Wang, Maggie Haitian, Leung, Chi-Ho, Chan, Eddie Shu-Yin, Chiu, Peter Ka-Fung, Yee, Chi-Hang, Wong, Hon-Ming, Hou, Simon See-Ming, Ng, Chi-Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732884/
https://www.ncbi.nlm.nih.gov/pubmed/30648670
http://dx.doi.org/10.4103/aja.aja_101_18
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author Teoh, Jeremy Yuen-Chun
Chan, Chi-Kwok
Wang, Maggie Haitian
Leung, Chi-Ho
Chan, Eddie Shu-Yin
Chiu, Peter Ka-Fung
Yee, Chi-Hang
Wong, Hon-Ming
Hou, Simon See-Ming
Ng, Chi-Fai
author_facet Teoh, Jeremy Yuen-Chun
Chan, Chi-Kwok
Wang, Maggie Haitian
Leung, Chi-Ho
Chan, Eddie Shu-Yin
Chiu, Peter Ka-Fung
Yee, Chi-Hang
Wong, Hon-Ming
Hou, Simon See-Ming
Ng, Chi-Fai
author_sort Teoh, Jeremy Yuen-Chun
collection PubMed
description It is largely unknown whether lower urinary tract symptoms (LUTS) or acute retention of urine (AROU) is linked to shorter life expectancy in men. We conducted a multicenter, retrospective database analysis of patients undergoing transurethral resection of prostate (TURP) to study their relationships. Multivariate Cox regression analysis and Kaplan–Meier analysis with stratification to age and indication of TURP were performed. We further performed an age- and sex-matched survival analysis with the general population using data from the Census and Statistics Department of the Hong Kong Special Administrative Region (Hong Kong, China). From January 2002 to December 2012, 3496 patients undergoing TURP were included in our study, with 1764 patients in the LUTS group and 1732 patients in the AROU group. Old age, ischemic heart disease, cerebrovascular accident, and AROU were risk factors of mortality. Patients aged <70 years (adjusted hazard ratio [HR]: 1.52, 95% confidence interval [CI]: 1.11–2.09, P = 0.010) and 70–80 years (adjusted HR: 1.39, 95% CI: 1.15–1.70, P = 0.001) in the AROU group had worse survival than those in the LUTS group, but such difference was not demonstrated in patients aged >80 years. Compared to the general population, younger patients in the LUTS group appeared to have better survival (<70 years, P = 0.091; 70–80 years, P = 0.011), but younger patients in the AROU group had worse survival (<70 years, P = 0.021; 70–80 years, P = 0.003). For patients aged >80 years, survival was similar with the general population in both the LUTS and AROU groups. In conclusion, AROU at young age was associated with mortality, while early detection and management of LUTS may improve survival.
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spelling pubmed-67328842019-09-20 Transurethral resection of prostate for acute urinary retention is linked to shorter survival in younger men Teoh, Jeremy Yuen-Chun Chan, Chi-Kwok Wang, Maggie Haitian Leung, Chi-Ho Chan, Eddie Shu-Yin Chiu, Peter Ka-Fung Yee, Chi-Hang Wong, Hon-Ming Hou, Simon See-Ming Ng, Chi-Fai Asian J Androl Original Article It is largely unknown whether lower urinary tract symptoms (LUTS) or acute retention of urine (AROU) is linked to shorter life expectancy in men. We conducted a multicenter, retrospective database analysis of patients undergoing transurethral resection of prostate (TURP) to study their relationships. Multivariate Cox regression analysis and Kaplan–Meier analysis with stratification to age and indication of TURP were performed. We further performed an age- and sex-matched survival analysis with the general population using data from the Census and Statistics Department of the Hong Kong Special Administrative Region (Hong Kong, China). From January 2002 to December 2012, 3496 patients undergoing TURP were included in our study, with 1764 patients in the LUTS group and 1732 patients in the AROU group. Old age, ischemic heart disease, cerebrovascular accident, and AROU were risk factors of mortality. Patients aged <70 years (adjusted hazard ratio [HR]: 1.52, 95% confidence interval [CI]: 1.11–2.09, P = 0.010) and 70–80 years (adjusted HR: 1.39, 95% CI: 1.15–1.70, P = 0.001) in the AROU group had worse survival than those in the LUTS group, but such difference was not demonstrated in patients aged >80 years. Compared to the general population, younger patients in the LUTS group appeared to have better survival (<70 years, P = 0.091; 70–80 years, P = 0.011), but younger patients in the AROU group had worse survival (<70 years, P = 0.021; 70–80 years, P = 0.003). For patients aged >80 years, survival was similar with the general population in both the LUTS and AROU groups. In conclusion, AROU at young age was associated with mortality, while early detection and management of LUTS may improve survival. Wolters Kluwer - Medknow 2019-01-15 /pmc/articles/PMC6732884/ /pubmed/30648670 http://dx.doi.org/10.4103/aja.aja_101_18 Text en Copyright: © The Author(s)(2019) http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Teoh, Jeremy Yuen-Chun
Chan, Chi-Kwok
Wang, Maggie Haitian
Leung, Chi-Ho
Chan, Eddie Shu-Yin
Chiu, Peter Ka-Fung
Yee, Chi-Hang
Wong, Hon-Ming
Hou, Simon See-Ming
Ng, Chi-Fai
Transurethral resection of prostate for acute urinary retention is linked to shorter survival in younger men
title Transurethral resection of prostate for acute urinary retention is linked to shorter survival in younger men
title_full Transurethral resection of prostate for acute urinary retention is linked to shorter survival in younger men
title_fullStr Transurethral resection of prostate for acute urinary retention is linked to shorter survival in younger men
title_full_unstemmed Transurethral resection of prostate for acute urinary retention is linked to shorter survival in younger men
title_short Transurethral resection of prostate for acute urinary retention is linked to shorter survival in younger men
title_sort transurethral resection of prostate for acute urinary retention is linked to shorter survival in younger men
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732884/
https://www.ncbi.nlm.nih.gov/pubmed/30648670
http://dx.doi.org/10.4103/aja.aja_101_18
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