Suberoylanilide hydroxamic acid upregulates histone acetylation and activates endoplasmic reticulum stress to induce apoptosis in HepG2 liver cancer cells

Suberoylanilide hydroxamic acid (SAHA) is a histone deacetylase inhibitor that has demonstrated clinical activity against various solid tumors. The aim of the present study was to explore the effects of SAHA on the apoptosis of HepG2 liver cancer cells, as well as the potential mechanisms involved i...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Xie, Rujia, Tian, Tian, Zheng, Lu, Tang, Lei, Cai, Shuang, Ma, Zihua, Yang, Ting, Han, Bing, Yang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732958/
https://www.ncbi.nlm.nih.gov/pubmed/31516571
http://dx.doi.org/10.3892/ol.2019.10705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732958/
https://www.ncbi.nlm.nih.gov/pubmed/31516571
http://dx.doi.org/10.3892/ol.2019.10705

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