Dendrobium alkaloids decrease Aβ by regulating α- and β-secretases in hippocampal neurons of SD rats

BACKGROUND: Alzheimer’s disease (AD) is the primary cause of dementia in the elderly. The imbalance between production and clearance of amyloid β (Aβ) is a very early, often initiating factor in AD. Dendrobium nobile Lindl. alkaloids (DNLA) extracted from a Chinese medicinal herb, which have been sh...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Juan, Huang, Nanqu, Zhang, Minghui, Nie, Jing, Xu, Yunyan, Wu, Qin, Shi, Jingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733236/
https://www.ncbi.nlm.nih.gov/pubmed/31534855
http://dx.doi.org/10.7717/peerj.7627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733236/
https://www.ncbi.nlm.nih.gov/pubmed/31534855
http://dx.doi.org/10.7717/peerj.7627

Ejemplares similares