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Dendrobium alkaloids decrease Aβ by regulating α- and β-secretases in hippocampal neurons of SD rats
BACKGROUND: Alzheimer’s disease (AD) is the primary cause of dementia in the elderly. The imbalance between production and clearance of amyloid β (Aβ) is a very early, often initiating factor in AD. Dendrobium nobile Lindl. alkaloids (DNLA) extracted from a Chinese medicinal herb, which have been sh...
Autores principales: | Huang, Juan, Huang, Nanqu, Zhang, Minghui, Nie, Jing, Xu, Yunyan, Wu, Qin, Shi, Jingshan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733236/ https://www.ncbi.nlm.nih.gov/pubmed/31534855 http://dx.doi.org/10.7717/peerj.7627 |
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