Cargando…

Premium ethylcellulose polymer based architectures at work in drug delivery

Premium ethylcellulose polymers are hydrophobic cellulose ether based biomaterials widely employed as biocompatible templates for the design of novel drug delivery systems. They are classified as United States Food and Drug Administration Generally-Recognized-As-Safe chemical substances and have bee...

Descripción completa

Detalles Bibliográficos
Autor principal: Adeleke, Oluwatoyin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733301/
https://www.ncbi.nlm.nih.gov/pubmed/31517288
http://dx.doi.org/10.1016/j.ijpx.2019.100023
_version_ 1783449956026155008
author Adeleke, Oluwatoyin A.
author_facet Adeleke, Oluwatoyin A.
author_sort Adeleke, Oluwatoyin A.
collection PubMed
description Premium ethylcellulose polymers are hydrophobic cellulose ether based biomaterials widely employed as biocompatible templates for the design of novel drug delivery systems. They are classified as United States Food and Drug Administration Generally-Recognized-As-Safe chemical substances and have been extensively utilized within the biomedical and pharmaceutical industries for over half a century. They have so far demonstrated the potential to modulate and improve the physiological performance of bioactives leading to the desired enhanced prophylactic and therapeutic outcomes. This review therefore presents a scholarly survey of inter-disciplinary developments focused on the functionalities of ethylcellulose polymers as biomaterials useful for the design of smart delivery architectures for relevant pharmacotherapeutic biomedical applications. Emphasis was placed on evaluating scientific resources related to recent advancements and future directions associated with its applications as delivery systems for drugs and biologics within the past decade thus complementing other specialized reviews showcasing the theme.
format Online
Article
Text
id pubmed-6733301
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-67333012019-09-12 Premium ethylcellulose polymer based architectures at work in drug delivery Adeleke, Oluwatoyin A. Int J Pharm X Article Premium ethylcellulose polymers are hydrophobic cellulose ether based biomaterials widely employed as biocompatible templates for the design of novel drug delivery systems. They are classified as United States Food and Drug Administration Generally-Recognized-As-Safe chemical substances and have been extensively utilized within the biomedical and pharmaceutical industries for over half a century. They have so far demonstrated the potential to modulate and improve the physiological performance of bioactives leading to the desired enhanced prophylactic and therapeutic outcomes. This review therefore presents a scholarly survey of inter-disciplinary developments focused on the functionalities of ethylcellulose polymers as biomaterials useful for the design of smart delivery architectures for relevant pharmacotherapeutic biomedical applications. Emphasis was placed on evaluating scientific resources related to recent advancements and future directions associated with its applications as delivery systems for drugs and biologics within the past decade thus complementing other specialized reviews showcasing the theme. Elsevier 2019-07-08 /pmc/articles/PMC6733301/ /pubmed/31517288 http://dx.doi.org/10.1016/j.ijpx.2019.100023 Text en http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Adeleke, Oluwatoyin A.
Premium ethylcellulose polymer based architectures at work in drug delivery
title Premium ethylcellulose polymer based architectures at work in drug delivery
title_full Premium ethylcellulose polymer based architectures at work in drug delivery
title_fullStr Premium ethylcellulose polymer based architectures at work in drug delivery
title_full_unstemmed Premium ethylcellulose polymer based architectures at work in drug delivery
title_short Premium ethylcellulose polymer based architectures at work in drug delivery
title_sort premium ethylcellulose polymer based architectures at work in drug delivery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733301/
https://www.ncbi.nlm.nih.gov/pubmed/31517288
http://dx.doi.org/10.1016/j.ijpx.2019.100023
work_keys_str_mv AT adelekeoluwatoyina premiumethylcellulosepolymerbasedarchitecturesatworkindrugdelivery