A linear polyethylenimine mediated siRNA-based therapy targeting human epidermal growth factor receptor in SPC-A1 xenograft mice

BACKGROUND: Linear polyethylenimine (LPEI) is considered as a desirable gene in vivo delivery system, but whether it could deliver the specific siRNA targeted EGFR to the tumor site to inhibit the growth of NSCLC xenograft in nude mice still needs to be examined. METHODS: In this study, LPEI/siRNA w...

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Detalles Bibliográficos
Autores principales: Zhang, Pinghai, Xu, Nuo, Zhou, Lei, Xu, Xin, Wang, Yuehong, Li, Ka, Zeng, Zhaochong, Wang, Xiangdong, Zhang, Xin, Bai, Chunxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733432/
https://www.ncbi.nlm.nih.gov/pubmed/27234384
http://dx.doi.org/10.1186/2213-0802-1-2

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