Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast

Genomic rearrangements (gross chromosomal rearrangements, GCRs) threatens genome integrity and cause cell death or tumor formation. At the terminus of linear chromosomes, a telomere-binding protein complex, called shelterin, ensures chromosome stability by preventing chromosome end-to-end fusions an...

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Detalles Bibliográficos
Autores principales: Irie, Hiroyuki, Yamamoto, Io, Tarumoto, Yusuke, Tashiro, Sanki, Runge, Kurt W., Ishikawa, Fuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733473/
https://www.ncbi.nlm.nih.gov/pubmed/31454352
http://dx.doi.org/10.1371/journal.pgen.1008335

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