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EV71 3C protease induces apoptosis by cleavage of hnRNP A1 to promote apaf-1 translation
Enterovirus 71 (EV71) induces apoptosis to promote viral particle release. Earlier work showed that EV71 utilizes its 3C protease to induce apoptosis in a caspase-3-dependent pathway, though the mechanism is unknown. However, work from Vagner, Holcik and colleagues showed that host protein heterogen...
Autores principales: | Li, Mei-Ling, Lin, Jing-Yi, Chen, Bo-Shiun, Weng, Kuo-Feng, Shih, Shin-Ru, Calderon, Jesse Davila, Tolbert, Blanton S., Brewer, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733512/ https://www.ncbi.nlm.nih.gov/pubmed/31498791 http://dx.doi.org/10.1371/journal.pone.0221048 |
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