Molecular basis for dyneinopathies reveals insight into dynein regulation and dysfunction

Cytoplasmic dynein plays critical roles within the developing and mature nervous systems, including effecting nuclear migration, and retrograde transport of various cargos. Unsurprisingly, mutations in dynein are causative of various developmental neuropathies and motor neuron diseases. These ‘dynei...

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Detalles Bibliográficos
Autores principales: Marzo, Matthew G, Griswold, Jacqueline M, Ruff, Kristina M, Buchmeier, Rachel E, Fees, Colby P, Markus, Steven M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733598/
https://www.ncbi.nlm.nih.gov/pubmed/31364990
http://dx.doi.org/10.7554/eLife.47246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733598/
https://www.ncbi.nlm.nih.gov/pubmed/31364990
http://dx.doi.org/10.7554/eLife.47246

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