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Molecular basis for dyneinopathies reveals insight into dynein regulation and dysfunction
Cytoplasmic dynein plays critical roles within the developing and mature nervous systems, including effecting nuclear migration, and retrograde transport of various cargos. Unsurprisingly, mutations in dynein are causative of various developmental neuropathies and motor neuron diseases. These ‘dynei...
Autores principales: | Marzo, Matthew G, Griswold, Jacqueline M, Ruff, Kristina M, Buchmeier, Rachel E, Fees, Colby P, Markus, Steven M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733598/ https://www.ncbi.nlm.nih.gov/pubmed/31364990 http://dx.doi.org/10.7554/eLife.47246 |
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