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A genetic selection reveals functional metastable structures embedded in a toxin-encoding mRNA

Post-transcriptional regulation plays important roles to fine-tune gene expression in bacteria. In particular, regulation of type I toxin-antitoxin (TA) systems is achieved through sophisticated mechanisms involving toxin mRNA folding. Here, we set up a genetic approach to decipher the molecular und...

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Detalles Bibliográficos
Autores principales: Masachis, Sara, Tourasse, Nicolas J, Lays, Claire, Faucher, Marion, Chabas, Sandrine, Iost, Isabelle, Darfeuille, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733600/
https://www.ncbi.nlm.nih.gov/pubmed/31411564
http://dx.doi.org/10.7554/eLife.47549