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Orbitrap journey: taming the ion rings

The establishment of the Orbitrap analyzer as a major player in mass spectrometry based proteomics is traced back to the first public presentation of this technology 20 years ago; when a proof-of-principle application led the way to further advancements and biological applications.

Detalles Bibliográficos
Autor principal: Makarov, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733855/
https://www.ncbi.nlm.nih.gov/pubmed/31501428
http://dx.doi.org/10.1038/s41467-019-11748-y
Descripción
Sumario:The establishment of the Orbitrap analyzer as a major player in mass spectrometry based proteomics is traced back to the first public presentation of this technology 20 years ago; when a proof-of-principle application led the way to further advancements and biological applications.