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A versatile platform technology for recombinant vaccines using non-propagative human parainfluenza virus type 2 vector

Ectopic protein with proper steric structure was efficiently loaded onto the envelope of the F gene-defective BC-PIV vector derived from human parainfluenza virus type 2 (hPIV2) by a reverse genetics method of recombinant virus production. Further, ectopic antigenic peptide was successfully loaded e...

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Detalles Bibliográficos
Autores principales: Ohtsuka, Junpei, Fukumura, Masayuki, Furuyama, Wakako, Wang, Shujie, Hara, Kenichiro, Maeda, Mitsuyo, Tsurudome, Masato, Miyamoto, Hiroko, Kaito, Aika, Tsuda, Nobuyuki, Kataoka, Yosky, Mizoguchi, Akira, Takada, Ayato, Nosaka, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733870/
https://www.ncbi.nlm.nih.gov/pubmed/31501502
http://dx.doi.org/10.1038/s41598-019-49579-y