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TRPM8-androgen receptor association within lipid rafts promotes prostate cancer cell migration

In prostate carcinogenesis, androgens are known to control the expression of the transient receptor potential melastatin 8 (TRPM8) protein via activation of androgen receptor (AR). Overexpression and/or activity of TRPM8 channel was shown to suppress prostate cancer (PCa) cell migration. Here we rep...

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Detalles Bibliográficos
Autores principales: Grolez, Guillaume P., Gordiendko, Dmitri V., Clarisse, Manon, Hammadi, Mehdi, Desruelles, Emilie, Fromont, Gaëlle, Prevarskaya, Natalia, Slomianny, Christian, Gkika, Dimitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733924/
https://www.ncbi.nlm.nih.gov/pubmed/31501416
http://dx.doi.org/10.1038/s41419-019-1891-8