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Polyphenol-rich extract induces apoptosis with immunogenic markers in melanoma cells through the ER stress-associated kinase PERK

Polyphenols elicit antitumor activities, in part, through the induction of anti- or pro-oxidant effects in cancer cells which promote priming of protective anti-tumor immunity. We recently characterized a polyphenol-rich extract from Caesalpinia spinosa (P2Et) that stimulates in vivo antitumor respo...

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Detalles Bibliográficos
Autores principales: Prieto, Karol, Cao, Yu, Mohamed, Eslam, Trillo-Tinoco, Jimena, Sierra, Rosa A., Urueña, Claudia, Sandoval, Tito Alejandro, Fiorentino, Susana, Rodriguez, Paulo C., Barreto, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733947/
https://www.ncbi.nlm.nih.gov/pubmed/31531232
http://dx.doi.org/10.1038/s41420-019-0214-2