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A case of pulmonary actinomycosis presented with endobronchial involvement

Pulmonary actinomycosis is a rare infectious disease, which is characterized by a wide range of symptoms and no specific imaging findings and may be confused with neoplasia, tuberculosis or pneumonia. Endobronchial involvement of actinomycosis may be caused by aspiration of foreign bodies or broncho...

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Autores principales: Oikonomidis, Petros, Fousekis, Fotios, Kotsaftis, Panagiotis, Pilios, Ioannis, Dimas, Dionysios, Giannoulis, Georgios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733995/
https://www.ncbi.nlm.nih.gov/pubmed/31516822
http://dx.doi.org/10.1016/j.rmcr.2019.100930
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author Oikonomidis, Petros
Fousekis, Fotios
Kotsaftis, Panagiotis
Pilios, Ioannis
Dimas, Dionysios
Giannoulis, Georgios
author_facet Oikonomidis, Petros
Fousekis, Fotios
Kotsaftis, Panagiotis
Pilios, Ioannis
Dimas, Dionysios
Giannoulis, Georgios
author_sort Oikonomidis, Petros
collection PubMed
description Pulmonary actinomycosis is a rare infectious disease, which is characterized by a wide range of symptoms and no specific imaging findings and may be confused with neoplasia, tuberculosis or pneumonia. Endobronchial involvement of actinomycosis may be caused by aspiration of foreign bodies or broncholithiasis and may bronchoscopically masquerade as malignancy. A case of 68-year-old man is reported, who presented with productive cough and fever and had no response to antibiotic therapy with moxifloxacin. Patchy air-space consolidation on left lower lobe was demonstrated on CT and flexible bronchoscopy revealed an endobronchial white necrotized mass, causing partial occlusion of bronchus and masquerading as lung cancer. Endobronchial actinomycosis was confirmed by biopsies of lesion, which revealed radiating filamentous colonies of Actinomyces and no evidence of malignancy. The patient was successfully treated with intravenous penicillin G for two weeks, followed by doxycycline per oral for six months, achieving full resolution of lesion on follow-up CT and bronchoscopy and no recurrence of symptoms.
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spelling pubmed-67339952019-09-12 A case of pulmonary actinomycosis presented with endobronchial involvement Oikonomidis, Petros Fousekis, Fotios Kotsaftis, Panagiotis Pilios, Ioannis Dimas, Dionysios Giannoulis, Georgios Respir Med Case Rep Case Report Pulmonary actinomycosis is a rare infectious disease, which is characterized by a wide range of symptoms and no specific imaging findings and may be confused with neoplasia, tuberculosis or pneumonia. Endobronchial involvement of actinomycosis may be caused by aspiration of foreign bodies or broncholithiasis and may bronchoscopically masquerade as malignancy. A case of 68-year-old man is reported, who presented with productive cough and fever and had no response to antibiotic therapy with moxifloxacin. Patchy air-space consolidation on left lower lobe was demonstrated on CT and flexible bronchoscopy revealed an endobronchial white necrotized mass, causing partial occlusion of bronchus and masquerading as lung cancer. Endobronchial actinomycosis was confirmed by biopsies of lesion, which revealed radiating filamentous colonies of Actinomyces and no evidence of malignancy. The patient was successfully treated with intravenous penicillin G for two weeks, followed by doxycycline per oral for six months, achieving full resolution of lesion on follow-up CT and bronchoscopy and no recurrence of symptoms. Elsevier 2019-08-29 /pmc/articles/PMC6733995/ /pubmed/31516822 http://dx.doi.org/10.1016/j.rmcr.2019.100930 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Oikonomidis, Petros
Fousekis, Fotios
Kotsaftis, Panagiotis
Pilios, Ioannis
Dimas, Dionysios
Giannoulis, Georgios
A case of pulmonary actinomycosis presented with endobronchial involvement
title A case of pulmonary actinomycosis presented with endobronchial involvement
title_full A case of pulmonary actinomycosis presented with endobronchial involvement
title_fullStr A case of pulmonary actinomycosis presented with endobronchial involvement
title_full_unstemmed A case of pulmonary actinomycosis presented with endobronchial involvement
title_short A case of pulmonary actinomycosis presented with endobronchial involvement
title_sort case of pulmonary actinomycosis presented with endobronchial involvement
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733995/
https://www.ncbi.nlm.nih.gov/pubmed/31516822
http://dx.doi.org/10.1016/j.rmcr.2019.100930
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