Accurate detection of m(6)A RNA modifications in native RNA sequences

The epitranscriptomics field has undergone an enormous expansion in the last few years; however, a major limitation is the lack of generic methods to map RNA modifications transcriptome-wide. Here, we show that using direct RNA sequencing, N(6)-methyladenosine (m(6)A) RNA modifications can be detect...

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Detalles Bibliográficos
Autores principales: Liu, Huanle, Begik, Oguzhan, Lucas, Morghan C., Ramirez, Jose Miguel, Mason, Christopher E., Wiener, David, Schwartz, Schraga, Mattick, John S., Smith, Martin A., Novoa, Eva Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734003/
https://www.ncbi.nlm.nih.gov/pubmed/31501426
http://dx.doi.org/10.1038/s41467-019-11713-9

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