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An Open Source Syringe Pump Controller for Fluid Delivery of Multiple Volumes

Syringe pumps are a necessary piece of laboratory equipment that are used for fluid delivery in behavioral neuroscience laboratories. Many experiments provide rodents and primates with fluid rewards such as juice, water, or liquid sucrose. Current commercialized syringe pumps are not customizable an...

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Detalles Bibliográficos
Autores principales: Amarante, Linda M., Newport, Jonathan, Mitchell, Meagan, Wilson, Joshua, Laubach, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734045/
https://www.ncbi.nlm.nih.gov/pubmed/31416819
http://dx.doi.org/10.1523/ENEURO.0240-19.2019
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author Amarante, Linda M.
Newport, Jonathan
Mitchell, Meagan
Wilson, Joshua
Laubach, Mark
author_facet Amarante, Linda M.
Newport, Jonathan
Mitchell, Meagan
Wilson, Joshua
Laubach, Mark
author_sort Amarante, Linda M.
collection PubMed
description Syringe pumps are a necessary piece of laboratory equipment that are used for fluid delivery in behavioral neuroscience laboratories. Many experiments provide rodents and primates with fluid rewards such as juice, water, or liquid sucrose. Current commercialized syringe pumps are not customizable and do not have the ability to deliver multiple volumes of fluid based on different inputs to the pump. Additionally, many syringe pumps are expensive and cannot be used in experiments with paired neurophysiological recordings due to electrical noise. We developed an open source syringe pump controller using commonly available parts. The controller adjusts the acceleration and speed of the motor to deliver three different volumes of fluid reward within one common time epoch. This syringe pump controller is cost effective and has been successfully implemented in rodent behavioral experiments with paired neurophysiological recordings in the rat frontal cortex while rats lick for different volumes of liquid sucrose rewards. Our syringe pump controller will enable new experiments to address the potential confound of temporal information in studies of reward signaling by fluid magnitude.
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spelling pubmed-67340452019-09-10 An Open Source Syringe Pump Controller for Fluid Delivery of Multiple Volumes Amarante, Linda M. Newport, Jonathan Mitchell, Meagan Wilson, Joshua Laubach, Mark eNeuro Open Source Tools and Methods Syringe pumps are a necessary piece of laboratory equipment that are used for fluid delivery in behavioral neuroscience laboratories. Many experiments provide rodents and primates with fluid rewards such as juice, water, or liquid sucrose. Current commercialized syringe pumps are not customizable and do not have the ability to deliver multiple volumes of fluid based on different inputs to the pump. Additionally, many syringe pumps are expensive and cannot be used in experiments with paired neurophysiological recordings due to electrical noise. We developed an open source syringe pump controller using commonly available parts. The controller adjusts the acceleration and speed of the motor to deliver three different volumes of fluid reward within one common time epoch. This syringe pump controller is cost effective and has been successfully implemented in rodent behavioral experiments with paired neurophysiological recordings in the rat frontal cortex while rats lick for different volumes of liquid sucrose rewards. Our syringe pump controller will enable new experiments to address the potential confound of temporal information in studies of reward signaling by fluid magnitude. Society for Neuroscience 2019-09-06 /pmc/articles/PMC6734045/ /pubmed/31416819 http://dx.doi.org/10.1523/ENEURO.0240-19.2019 Text en Copyright © 2019 Amarante et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Open Source Tools and Methods
Amarante, Linda M.
Newport, Jonathan
Mitchell, Meagan
Wilson, Joshua
Laubach, Mark
An Open Source Syringe Pump Controller for Fluid Delivery of Multiple Volumes
title An Open Source Syringe Pump Controller for Fluid Delivery of Multiple Volumes
title_full An Open Source Syringe Pump Controller for Fluid Delivery of Multiple Volumes
title_fullStr An Open Source Syringe Pump Controller for Fluid Delivery of Multiple Volumes
title_full_unstemmed An Open Source Syringe Pump Controller for Fluid Delivery of Multiple Volumes
title_short An Open Source Syringe Pump Controller for Fluid Delivery of Multiple Volumes
title_sort open source syringe pump controller for fluid delivery of multiple volumes
topic Open Source Tools and Methods
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734045/
https://www.ncbi.nlm.nih.gov/pubmed/31416819
http://dx.doi.org/10.1523/ENEURO.0240-19.2019
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